My personal PSA movements
I have interesting news to share with
those who chose Radiotherapy combined with Hormone Therapy treatments.
I participate in US TOO Prostrate
Cancer Support Group - Inspire. Visit the group here http://www.inspire.com/groups/us-too-prostate-cancer/
During one dialog I had a reply from
Mr Richard Davis who had an interesting theory to share. That is our PSA will
rise after we finished out Hormone treatment, AND it will rise until a certain
point when it will possible plateau out or return back to zero level.
He showed me a sketch graph
illustrating the theory or Hypothesis developed by a prominent Oncologist /
Radiologist in MD Andersons Hospital.
I produced my own graph with EXCEL as
shown above with explanations to the theory.
X = Time line for 4 years, the normal
time for Radiation to continue to be effective is between 3 to 5 years or even
more years for some.
Y = PSA levels.
RED LINE is PSA decline due to
Radiation without additional treatment of ADT.
BLUE lines show PSA rise for those
people after stopping ADT at 12 months, 24 months and 36 months. I stopped
after 36 months.
I started off with PSA = 27 ng/ml
with my last ADT injection on 36 months. My PSA started to rise again after
stopping Zoladex.
My PSA level is now 0.18 ng/ml after
18 months from stopping Zoladex injections.
My PSA will be expected to rise until
it meets the RED PSA line created by Radiation treatment AND thence will start
to decline ALONG the Red line.
Please note PSA bumps are experienced
with mostly Brachytherapy. I did not get the bump after 12 - 24 months after my
radiation.
I hope this theory will hold true as
Mr Richard has assured me that he himself and others had experienced this trend
of PSA leveling out and then returning back to zero.
A paper will be presented on this
hypothesis hopefully soonest.
Take care all,
Allen Lai
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