As our line of defenses in treatments fail, PCa advances into a
new state of growth. This is generally known as advanced PCa. Advanced PCa is
known to be in any one of these state:
Metastatic,
asymptomatic, hormone-refractory prostate cancer.
Metastatic
castrate-resistant (mCRPC).
Androgen-independent
(AI) prostate cancer.
Our Oncologist will have to determine the state of our advanced
PCa in order to prescribe the next line of defense. Drugs and protocols for advanced
PCa are actively on-going. Immunotherapy leads in this area of treatment.
Cancer patients need to know that Radiotherapy can be done after
Prostatectomy, but Prostatectomy cannot be done after Radiotherapy. How ever Hormone
Therapy is the standard treatment protocol after either treatment fails.
The following FDA
approved drugs may be prescribed in addition to hormone therapy:
Abiraterone (Zytiga) and prednisone.
Enzalutamide (Xtandi).
Radium-223 (Xofigo) for men with cancer that has spread to
the bone.
Docetaxel (Docefrez, Taxotere) and prednisone.
Sipuleucel-T (Provenge) for men who have few or no symptoms from
the cancer
Cabazitaxel (Jevtana) and prednisone for men with prostate cancer
that has worsened while receiving docetaxel.
Mitoxantrone (Novantrone) plus prednisone.
Bicalutamide (Casodex), flutamide (Eulexin), nilutamide
(Nilandron), which are all types of anti-androgens.
Ketoconazole (Nizoral, Xolegel).
Low-dose corticosteroids.
Take care
Allen Lai
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